Product Description

CD275 Recombinant Protein

Catalogue Number: NCP0384-500, NCP0384-1000

Sizes: 500ug, 1mg

Swiss-Prot: O75144

Host: E.coli

Tag: His-tag

AA Sequence: DTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKt VVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDt VFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLt VGSQTGNDIGERDKITENPVSTGEKNAAT

Restriction Sites: NdeI-XhoI

Background: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.

Soluble: PBS, 4M Urea, PH7.4

Purification and Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Expression Vector: pet-22b(+)

BioWorld Molecular Weight: ~30kDa

Notes: For research use only, not for use in diagnostic procedure.