CD284 Polyclonal Antibody - E-AB-70375

CD284 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70375-60, E-AB-70375-120, E-AB-70375-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD284

Target Synonym: ARMD10; CD284; CD284 antigen; Homolog of Drosophila toll; hToll; TLR 4; TLR4; TLR4; TOLL; Toll like receptor 4; Toll-like receptor 4

Research Areas: Cancer, Cardiovascular, Immunology, Microbiology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O00206,Q9QUK6,Q9QX05

Background: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Concentration: 0.9 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse TLR4.

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1::500-1:2000

Calculated MW: 95kDa

Observed MW: 95kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only