Product Description

CD294 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67174-50, BS67174-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may resμlt in pertussis toxin-sensitive decreases in cAMP levels and Ca2+mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regμlated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regμlation and allergic/inflammation responses.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: CRTH2, DL1R, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecμle expressed on Th2 cells, G-protein coupled receptor 44, CD294

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD294. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 135% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of CD294 protein.

Molecular Weight: ~ 43 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y5Y4

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only