CD2AP Polyclonal Antibody - E-AB-16309

CD2AP Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16309-60, E-AB-16309-120, E-AB-16309-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD2AP

Target Synonym: Adapter protein CMS; AL024079; C78928; Cas ligand with multiple SH3 domains; CD2 associated protein; CD2-associated protein; CD2AP; CD2AP; CMS; Mesenchyme to epithelium transition protein with SH3 domains 1; METS 1; Mets1

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9Y5K6

Background: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Concentration: 0.2 mg/mL

Immunogen: Synthetic peptide of human CD2AP

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:100-1:300

Calculated MW: 71kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only