CD3-ε rabbit pAb - ES7974

CD3-ε rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7974-50, ES7974-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],

Alternate Name: CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD antigen CD3e

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse; ; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human CD3-epsilon. AA range:22-71

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 21kD

Human Gene ID: 916

Human SWISS Prot NO: P07766

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only