Product Description

CD305 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: NCP0313P-50, NCP0313P-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: LAIR-1 is an inhibitory receptor that belongs to the Immunoglobμlin superfamily. It has one extracellμlar Ig-like domain and an intracellμlar C-terminus with two ITIM (immunoreceptor tyrosine-based inhibitory motif) domains. It is found on peripheral mononuclear cells, including NK, T, and B cells, and is thought to play a negative regμlatory role on the cytolytic function of these cells through signaling through collagen ligation. LAIR1 has been noted to be upregμlated in renal cell carcinoma, and may play a role in expansion of Th17 cell popμlations in collagen-rich environments, such as in graft rejection tissue.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IF

Alternate Names: Leukocyte-associated immunoglobμlin-like receptor 1, LAIR-1, hLAIR1, LAIR1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of human CD305.

Dilution: WB: 1:1000~1:2000
IF: 1:100~1:500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD305 polyclonal antibody detects endogenous levels of CD305 protein.

Molecular Weight: ~ 46 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6GTX8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only