Product Description

CD31 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10694-50, MB10694-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P16284

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 83 kDa; Observed MW: 130 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD31 in Jurkat lysates using CD31 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CD31 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31

Immunogen: A synthetic peptide of human CD31

Conjugate: Unconjugated

Modification: Unmodified