Product Description

CD31 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16501-50, BZ16501-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P16284

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-F, IHC-P, ICC/IF, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 83 kDa; Observed MW: 83 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD31 in HepG2, K562, L929, mouse brain lysates using CD31 antibody., Immunofluorescence analysis of CD31 in HeLa using CD31 antibody. The picture on the right is blocked using synthesized peptide., Immunohistochemistry analysis of paraffin-embedded CD31 in paraffin-embedded Human kidney using CD31 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31

Immunogen: synthesized peptide of human PECAM-1. AA range:686-735

Conjugate: Unconjugated

Modification: Unmodified