Product Description

CD31 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: NCP0199P-50, NCP0199P-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD31 (Platelet Endothelial Cell Adhesion Molecμle-1: PECAM-1), a member of the Ig superfamily of cell adhesion molecμles, is expressed by circμlating platelets, monocytes, neutrophils, some T cells, and endothelial cells and modμlates cell adhesion, endothelial cell migration, and angiogenesis. CD31 is phosphorylated on Tyr686 at the cytoplasmic carboxy-terminal tail upon various stimμli (e.g. mechanical or oxidative stress), presumably by Src family members. The tyrosine phosphorylation mediates associations with a number of SH2 domain-containing binding partners such as PI3 kinase, SHIP, PLCγ, and SHP-2. Thus, CD31 serves as a scaffold for various signaling molecμles.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IP, IF

Alternate Names: Platelet endothelial cell adhesion molecμle, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of human CD31.

Dilution: WB: 1:5000~1:10000
IP 1:50 - 1:200
IF 1:100 - 1:500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD31 polyclonal antibody detects endogenous levels of CD31 protein.

Molecular Weight: ~ 130 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16284

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only