Product Description

CD314 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23032-50, RA23032-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: killer cell lectin like receptor K1 (KLRK1) Homo sapiens Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section), ELISA

Alternate Names: NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1;NK cell receptor D;NKG2-D-activating NK receptor;CD antigen CD314)

Clonality: Polyclonal

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000

Storage: -20°C/1 year

Human Gene ID: 100528032

Human SwissProt Number: P26718

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only