CD32-C Polyclonal Antibody-BS5656

CD32-C Polyclonal Antibody

Catalogue Numbers: BS5656-50, BS5656-100

Sizes: 50µl, 100µl

Alternative Name: Low affinity immunoglobulin gamma Fc region receptor II-c; IgG Fc receptor II-c; CDw32; Fc-gamma RII-c; Fc-gamma-RIIc; FcRII-c; CD32; FCGR2C; FCG2; IGFR2; Fcγ-RIIc; Fcγ RIIc

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P31995

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: CD32 (also designated Fc γ RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells. CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C. These isoforms are designated CD32-A, CD32-B1, CD32-B3, and CD32-C. All isoforms are present on monocytes, placental trophoblasts and endothelial cells. In addition, the CD32-B forms are present on B lymphocytes, and the CD32-A and CD32-C forms are found on neutrophils.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD32-C polyclonal antibody detects endogenous levels of CD32-C protein.

Bioworld Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD32-C polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: PC12 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 278-323 of Human CD32-C.

Conjugate: Unconjugated

Modification: Unmodified