Product Description

CD354 Polyclonal Antibody

Catalogue Numbers: BS62551-50, BS62551-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NP99

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: TREM-1 (triggering receptor expressed on myeloid cells-1) is expressed in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. TREM-1 is a glycoprotein that is reduced by deglycosylation, in agreement with the predicted molecular mass. TREM-1 is an activating receptor of the Ig superfamily that is expressed on human myeloid cells, selectively expressed on blood neutrophils and a subset of monocytes, and is upregulated by bacterial LPS. Immunoblot analysis shows that TREM-1 is associated with DAP12, a molecule frequently associated with activating receptors. TREM-1 and the myeloid DAP12-associating lectin (MDL-1) are recently identified receptors which associate non-covalently with DAP12 to form receptor complexes that are involved in monocytic activation and inflammatory response.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD354 polyclonal antibody detects endogenous levels of CD354 protein.

Extra Notes: Western blot (WB) analysis of CD354 polyclonal antibody at 1:500 dilution
LaneA:U-87MG whole cell lysate
LaneB:A549 whole cell lysate
LaneC:L02 whole cell lysate

Bioworld Molecular Weight: ~ 17, 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354; TREM1

Immunogen: Synthetic peptide, corresponding to Human CD354.

Conjugate: Unconjugated

Modification: Unmodified