CD38 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23049-50, RA23049-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: CD38 molecule (CD38) Homo sapiens The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: CD38, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10, CD38 Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 35 Protein Molecular Weight (kDa): 35 Storage: -20°C/1 year Human Gene ID: 952 Human SwissProt Number: P28907 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only