CD3D Polyclonal Antibody - E-AB-60274

CD3D Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60274-60, E-AB-60274-120, E-AB-60274-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD3D

Target Synonym: CD3D; CD3-DELTA; IMD19; T3D

Research Areas: Cancer, Immunology, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P04234

Background: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CD3D (NP_000723.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100 IF 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only