CD3E Monoclonal Antibody - BT-MCA4396

CD3E Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4396-50, BT-MCA4396-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Research Areas: Immunology

Target Protein: CD3E

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4E2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD3E

Immunogen: Purified recombinant fragment of CD3E expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 23kDa

UniProt Accession: P07766

Synonyms: T3E, TCRE, FLJ18683, CD3E

GeneID: 916

Research Use Only