CD3E Polyclonal Antibody - E-AB-60431

CD3E Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60431-60, E-AB-60431-120, E-AB-60431-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD3E

Target Synonym: CD3E; IMD18; T3E; TCRE; CD3e molecule

Research Areas: Immunology, Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P07766

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CD3E (NP_000724.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only