CD41 Monoclonal Antibody (Q90) - BT-MCA0306

CD41 Monoclonal Antibody (Q90)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0306-20, BT-MCA0306-50, BT-MCA0306-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.

Research Areas: Immunology; Stem cells; Cardiovascular

Target Protein: ITGA2B

Applications: IHC-p, IF

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Integrin alpha-IIb

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 113391

UniProt Accession: Human: P08514; Mouse: Q9QUM0

Synonyms: ITGA2B; GP2B; ITGAB; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41

GeneID: Human: 3674; Mouse: 16399

Research Use Only