Product Description

CD45 (8C1) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB3167-50, MB3167-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regμlator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modμlates LYN activity.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IHC-F, IHC-P, ICC/IF

Alternate Names: GP180, L CA, CD45 antigen

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic Peptide of CD45

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Purification: Affinity Purified

Specificity: IgG1

Molecular Weight: Calcμlated MW: 145 kDa, Observed MW: 145 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P06800

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only