CD45 Mouse mAb - EM1046

CD45 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1046-50, EM1046-100

Citations, Manuals and MSDS Available upon request.

Background: CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45.

Alternate Name: B220, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200

Source: Mouse

Applications: WB

Dilution: WB 1:2, 000 IHC 1:200

Reactivity: Human

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 147kDa

Human Gene ID: 5788

Human SWISS Prot NO: P08575

Subcellular Location: Membrane

Research Use Only