Product Description

CD45 Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40103-50, BS40103-100

Swiss-Prot: P08575

Host: Rabbit

CD45 Rabbit Monoclonal Antibody -BS40103

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human

Applications: WB, IHC ICC/IF FC

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:100 FC 1:20

Background: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).

Purification and Purity: Affinity-chromatography

Specificity: CD45 Antibody detects endogenous levels of total CD45

Bioworld Molecular Weight: 150kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD45 expression in Jurkat cell lysate., Immunohistochemical analysis of paraffin-embedded human spleen, using CD45 Antibody.

Alternative Name: CD45; B220; GP180; LCA; PTPRC; T200 leukocyte common antigen;

Immunogen: A synthesized peptide derived from human CD45

Modification: Unmodified

Conjugate: Unconjugated