CD49c HC Polyclonal Antibody-BS67676

CD49c HC Polyclonal Antibody

Catalogue Numbers: BS67676-50, BS67676-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P26006

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of CD49c HC protein.

Extra Notes: Western blot analysis of CD49c HC expression in mouse lung (A), mouse kidney (B), rat kidney (C) whole cell lysates.

Bioworld Molecular Weight: ~ 250 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: MSK18; Integrin alpha-3; CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alpha; CD49c

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD49c HC. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified