CD5 Mouse mAb - EM1071

CD5 Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1071-50, EM1071-100

Citations, Manuals and MSDS Available upon request.

Background: CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.

Alternate Name: CD5 molecule, LEU1, Lymphocyte antigen T1/Leu 1, T1

Source: Mouse

Applications: IHC

Dilution: IHC 1:100-200

Reactivity: Human, Rat, Mouse

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Human Gene ID: 921

Human SWISS Prot NO: P06127

Subcellular Location: Membrane

Research Use Only