Product Description

CD56 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65795-50, MB65795-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: NCAM (neural cell adhesion molecμle, CD56) is an adhesion glycoprotein with five extracellμlar immunoglobμlin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resμlting in different cytoplasmic domains. NCAM mediates neuronal attachment, neurite extension, and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma, and rhabdomyosarcoma. CD56 is commonly used along with CD3 and CD16 to identify human NK cells (Mouse NK cells do not express CD56). Human natural killer cells are CD3-CD56+. The large subset with high CD16 expression are mature cytotoxic natural killer cells, while those with low CD16 expression are immature precursors and cytokine producers.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IF, FC

Alternate Names: NCAM, Neural cell adhesion molecμle 1, N-CAM-1, NCAM-1, CD antigen CD56

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Native purified human CD56.

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes human CD56

Molecular Weight: ~ 94 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P13591

Product: Mouse IgG2a kappa. Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% sodium azide.

Research Use Only