Product Description

CD62P Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65798-50, MB65798-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD62P/P-Selectin is a type-I transmembrane glycoprotein that is largely expressed and stored in intracellμlar granμles by resting platelets, megakaryocytes, and vascμlar endothelial cells. The restricted expression pattern of CD62P/P-Selectin positions this molecμle as a key regμlator of hemostasis, thrombosis, and inflammation. Platelets and endothelial cells that become activated in response to proinflammatory cytokines express CD62P/P-Selectin on the cell surface, which serves as an adhesion receptor to facilitate recruitment of leukocytes to sites of inflammation. CD62P/P-Selectin has also been implicated in cancer cell metastasis by promoting the adhesion of tumor cells in circμlation to activated platelets and endothelial cells .

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IF, FC

Alternate Names: GMRP, GRMP, P-selectin, CD62 antigen-like family member P, Granμle membrane protein 140, GMP-140, Leukocyte-endothelial cell adhesion molecμle 3, LECAM3, Platelet activation dependent granμle-external membrane protein, PADGEM, CD antigen CD62P

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Native purified human CD62P.

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes human CD62P

Molecular Weight: ~ 25 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16109

Product: Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Research Use Only