CD62P Polyclonal Antibody-BS90253

CD62P Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90253-50, BS90253-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P16109(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

All Applications: WB:1:1,000-1:2,000
IHC:1:50-1:200

Background: Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CD62P polyclonal antibody detects endogenous levels of CD62P protein.

Bioworld Molecular Weight: 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD62P on different cells lysates using anti-CD62P antibody at 1/500 dilution.
Positive control: Line1: HUVEC Line2: Human placenta, Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD62P antibody. Counter stained with hematoxylin.

Alternative Name: GMP-140, LECAM3, PADGEM, SELP, Antigen CD62, CD62, CD62 antigen-like family member P, CD62P, GMP 140, GMP-140, GMP140, GMRP, Granule membrane protein 140, Granulocyte membrane protein, GRMP, LECAM 3, LECAM3, Leukocyte endothelial cell adhesion molecule 3, Leukocyte-endothelial cell adhesion molecule 3, LYAM3, P Selectin, P-selectin, PADGEM, Platelet activation dependent granule-external membrane protein, Platelet alpha granule membrane protein, PSEL, Selectin P (granule membrane protein 140kDa, antigen CD62), SELP,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified