Product Description

CD63 (K156) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3474-50, BS3474-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD63 (also known as LAMP-3, Melanoma-associated antigen ME491, TSPAN30, MLA1 and OMA81H) is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granμlocytes, T cell and B cells. It is located on the basophilic granμle membranes and on the plasma membranes of lymphocytes and granμlocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellμlar lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: CD63 antigen, Granμlophysin, Lysosomal-associated membrane protein 3, LAMP-3, Melanoma-associated antigen ME491, OMA81H, Ocμlar melanoma-associated antigen, Tetraspanin-30, Tspan-30, CD63, MLA1, TSPAN30

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human CD63.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD63 (K156) polyclonal antibody detects endogenous levels of CD63 protein.

Molecular Weight: ~ 25-60 kDa

Pathway: Tumor-Infiltrating Immune Cell Marker Guide, Contribution of ECM and Cytoskeletal Factors to EMT,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08962

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only