CD68 Monoclonal Antibody (6F3)
Sizes: 50μL, 100μL
Catalogue Number: RA10548-50, RA10548-100
Citations, Manuals and MSDS Available upon request.
Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: WB 500-2000 1:200 IF 1:50-200
Alternative Names: CD68; Macrosialin; Gp110; CD68
Background: CD68 molecule(CD68) Homo sapiens This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],
Applications: IHC-P; IF/ICC
Species Cross-Reactivity: Human; Mouse; Rat
Molecular Weight: 37
GeneID (Human): 968
Protein MW (KDa): 37
SWISS: P34810
Source: Mouse
Research Use Only