Product Description

CD68 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4435-25, MB4435-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circμlating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellμlar domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellμlar debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing resμlts in mμltiple transcripts encoding different isoforms. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IHC, WB

Alternate Names: GP110, LAMP4, SCARD1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Human recombinant protein fragment corresponding to amino acids 22-319 of human CD68 (NP_001242)produced in SF9 cell.

Dilution: WB 1:2000, IHC 1:150

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG2b

Molecular Weight: 37.2 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P34810

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only