CD68 Polyclonal Antibody - RA20941

CD68 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20941-50, RA20941-100

Citations, Manuals and MSDS Available upon request.

Background: CD68 molecule (CD68) Homo sapiens This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: CD68; Macrosialin; Gp110; CD68

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 968

Protein MW (KDa): 37

SWISS: P34810

Source: Rabbit

Research Use Only