Product Description

CD73 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65802-50, MB65802-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ecto-5'-nucleotidase (NT5E, also called CD73) is a 70 kDa glycosyl phosphatidylinositol-anchored, membrane-bound glycoprotein that catalyzes the hydrolysis of extracellμlar nucleoside monophosphates into bioactive nucleosides. NT5E catalyzes the terminal step of extracellμlar adenosine formation from adenosine monophosphate, which drives the regμlation of extracellμlar adenosine levels and the downstream activation of the four G protein-coupled adenosine receptors. Binding of hypoxia-inducible factor (HIF-1) to the NT5E gene promoter leads to upregμlation of NT5E during hypoxia. The biological roles of NT5E include lymphocyte adhesion, fibrosis, and the regμlation of nociception.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IF, FC

Alternate Names: NT5, NTE, 5'-nucleotidase, 5'-NT, Ecto-5'-nucleotidase, CD antigen CD73

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Native purified human CD73.

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes human CD73

Molecular Weight: ~ 63 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P21589

Product: Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Research Use Only