Product Description

CD8 alpha Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46049-50, BS46049-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecμles. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobμlin variable light chains. This gene encodes the CD8 alpha chain. Mμltiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: IHC, ICC/IF, FC

Alternate Names: CD8, p32, Leu2, IMD116, CD8alpha

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human CD8 alpha

Dilution: IHC: 1:200-1:2000 ICC/IF: 1:100 FC: 1:200-1:500

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 26 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01732

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only