CD8 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65560-50, BS65560-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecμles. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobμlin variable light chains. This gene encodes the CD8 alpha chain. Mμltiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. Category: Primary Antibody Reactivity: Rat Host: Rabbit Applications: WB Alternate Names: CD8 antigen, alpha polypeptide (p32), CD8a, CD8a antigen, CD8a molecμle, CD8A_RAT, Leu2, Leu2 T lymphocyte antigen, MAL, OKT8 T cell antigen, p32, T cell antigen Leu2, T cell co receptor, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, T8 T cell antigen. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from rat CD8:41-140/236 Dilution: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations shoμld be determined by the end user. Purification: affinity purified by Protein A Specificity: CD8 polyclonal Antibody detects endogenous levels of CD8 protein. Molecular Weight: ~40kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: P07725 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only