CD82 Polyclonal Antibody - E-AB-67224

CD82 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67224-60, E-AB-67224-120, E-AB-67224-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD82

Target Synonym: CD82; 4F9; C33; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27

Research Areas: Immunology,Epigenetics and Nuclear Signaling,Cancer

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P27701

Background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human CD82 (NP_002222.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only