Product Description

CD86 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23108-50, RA23108-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD86 molecule (CD86) Homo sapiens This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: T-lymphocyte activation antigen CD86 (Activation B7-2 antigen;B70;BU63;CTLA-4 counter-receptor B7.2;FUN-1;CD antigen CD86)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Storage: -20°C/1 year

Human Gene ID: 942

Human SwissProt Number: P42081

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only