Product Description

CD97 alpha Polyclonal Antibody

Catalogue Numbers: BS62561-50, BS62561-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P48960

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD97 alpha polyclonal antibody detects endogenous levels of CD97 alpha protein.

Extra Notes: Western blot (WB) analysis of CD97 alpha polyclonal antibody at 1:500 dilution
LaneA:Jurkat whole cell lysate
LaneB:HCT116 whole cell lysate
LaneC:H9C2 whole cell lysate

Bioworld Molecular Weight: ~ 92 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: CD97; TM7LN1

Immunogen: Synthetic peptide, corresponding to Human CD97 alpha.

Conjugate: Unconjugated

Modification: Unmodified