Cdc25A (phospho Ser178) rabbit pAb - ES8130

Cdc25A (phospho Ser178) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8130-50, ES8130-100

Citations, Manuals and MSDS Available upon request.

Background: cell division cycle 25A (CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternate Name: CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser178. AA range:144-193

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 59kD

Human Gene ID: 993

Human SWISS Prot NO: P30304

Subcellular Location: intracellular, nucleus, nucleoplasm, cytoplasm, cytosol,

Research Use Only