Cdc25A Polyclonal Antibody - BT-AP01577

Cdc25A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01577-20, BT-AP01577-50, BT-AP01577-100

Citations, Manuals and MSDS Available upon request.

Background: CDC25A (cell division cycle 25A) is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cell Biology

Target Protein: CDC25A

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Cdc25A Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 59087

UniProt Accession: Human: P30304; Mouse: P48964; Rat: P48965

Synonyms: CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A

GeneID: Human: 993; Rat: 171102

Research Use Only