Cdc27 Polyclonal Antibody-BS90269

Cdc27 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90269-50, BS90269-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P30260(Human) A2A6Q5(Mouse) Q4V8A2(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB:1:1,000-1:5,000

Background: n the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with Hsp90. Cdc34, Cdc27 and Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cdc27 on differentLysates using anti-Cdc27 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela Lane 2: K562

Bioworld Molecular Weight: 92 kDa

Specificity: Cdc27 polyclonal antibody detects endogenous levels of Cdc27 protein.

Alternative Name: APC3, CDC27Hs, CDC27, ANAPC3, Anaphase Promoting Complex 3, Anaphase promoting complex protein 3, Anaphase Promoting Complex Subunit 3, Anaphase-promoting complex subunit 3, APC 3, APC3, Cdc 27, Cdc27, CDC27 homolog, CDC27, CDC27Hs, Cell Division Cycle 27, Cell division cycle protein 27 homolog, D0S1430E, D17S978E, H NUC, H-NUC, HNUC, Nuc2 homolog,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified