Product Description

CDC7 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10712-50, MB10712-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O00311

Host: Rabbit

Reactivity: Human,Hamster

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: DNA replication in eukaryotic cells is dependent on the phosphorylation of the pre-replicative complex (preRC) at the origin of replication. Two complexes of proteins mediate this event, the cyclin dependent kinase (CDK) complex, and the Cdc7 kinase-ASK complex. Human Cdc7 kinase consists of 574 amino acids with a molecular weight of 55 kDa. The activity of Cdc7 kinase oscillates during cell cycle. The major targets of Cdc7 kinase are proteins that belong to the MCM complex (mini chromosome maintenance proteins).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CDC7 in Hela, CHO-K1, JurkatLysates using CDC7 antibody.

Bioworld Molecular Weight: Calculated MW: 64 kDa; Observed MW: 64 kDa

Specificity: IgG

Alternative Name: Cell division cycle 7-related protein kinase; EC 2.7.11.1; CDC7-related kinase; HsCdc7; huCdc7; CDC7; CDC7L1; Hsk1; CDC7 kinase

Immunogen: Recombinant protein of human CDC7

Conjugate: Unconjugated

Modification: Unmodified