CDCP1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB9176-50, MB9176-100
Product: Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9H5V8(Human) Q5U462(Mouse)
Host: Mouse
Reactivity: Human, Mouse, Rat
Applications: WB, IHC ICC
All Applications: WB:1:500
ICC:1:50
IHC:1:50-1:100
Background: CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.
Purification and Purity: Protein affinity purified.
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: CDCP1 monoclonal antibody detects endogenous levels of CDCP1 protein.
Bioworld Molecular Weight: 92/72/37 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of CDCP1 on K562 cell lysates using anti-CDCP1 antibody at 1/200 dilution., ICC staining CDCP1 (green) in LOVO cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: SIMA135, CD318, CDCP1, TRASK, 9030022E12Rik, AA409659, CD 318, CD_antigen=CD318, CD318, CD318 antigen, CDCP 1, Cdcp1, CDCP1, CUB domain containing protein 1, CUB domain-containing protein 1, E030027H19Rik, FLJ13772, FLJ22375, FLJ22969, Membrane glycoprotein gp140, MGC31813, OTTHUMP00000164120, OTTHUMP00000209568, RGD1305578, SIMA 135, SIMA135, Subtractive immunization M plus HEp3 associated 135 kDa protein, Subtractive immunization M plus HEp3-associated 135 kDa protein, Transmembrane and associated with src kinases, TRASK,
Immunogen: Recombinant protein.
Conjugate: Unconjugated
Modification: Unmodified