Product Description

CDK11A/B Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16328-60, E-AB-16328-120, E-AB-16328-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CDK11A/CDK11B

Target Synonym: CDC2L2; CDC2L3; p58GTA; PITSLRE; CDK11-p46; CDK11-p58; CDK11-p110 / p58; PK58; CDK11; CLK-1; CDC2L1; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9UQ88,P21127

Background: Cyclin-dependent kinases (CDKs)are a family ofproteinkinasesfirst discovered for their role in regulating thecell cycle. They are also involved in regulatingtranscription, mRNA processing, and the differentiation of nerve cells. They are present in all knowneukaryotes, and their regulatory function in thecell cyclehas been evolutionarily conserved. CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.

Concentration: 0.6 mg/mL

Immunogen: Synthetic peptide of human CDK11A/CDK11B

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only