CDK5 Mouse Monoclonal Antibody (3D1) - RA10961

CDK5 Mouse Monoclonal Antibody (3D1)

Size: 50μL, 100μL

Catalogue Numbers: RA10961-50, RA10961-100

Citations, Manuals and MSDS Available upon request.

Background: cyclin dependent kinase 5 (CDK5) Homo sapiens This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants.

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.04% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC-p; WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 1020

Protein MW (KDa): 33

SWISS: Q00535

Source: Mouse

Research Use Only