Product Description

CDK7 (N166) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1524-50, BS1524-100

Sizes: 50µl, 100µl

Swiss-Prot: P50613

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

Background: Cdk7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. Cdk7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CDK7 (N166) polyclonal antibody detects endogenous levels of CDK7 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CDK7 (N166) pAb at 1:500 dilution
Lane 1: A375 whole cell lysate (40ug)
Lane 2: A549 whole cell lysate (40ug)
Lane 3: HCC827 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of CDK7 (N166) pAb in paraffin-embedded human breast tissue.

Bioworld Molecular Weight: ~ 39 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Cyclin-dependent kinase 7; 39 kDa protein kinase; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit; CDK7; CAK; CAK1; CDKN7; MO15; STK1

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human CDK7.

Conjugate: Unconjugated

Modification: Unmodified