CDK7 Polyclonal Antibody - E-AB-65984

CDK7 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-65984-60, E-AB-65984-120, E-AB-65984-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CDK7

Target Synonym: CDK7; CAK; CAK1; CDKN7; HCAK; MO15; STK1; p39MO15

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P50613

Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CDK7 (NP_001790.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only