CDKN1C/p57 Kip2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2060-20, A2060-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 32kDa
Observed Molecular Weight: 57kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 1028
SWISS: P49918
Alternate Names: BWS; WBS; p57; BWCR; KIP2; p57Kip2; CDKN1C/p57 Kip2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Kinase, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors.
NCBI Alias: CDKN1C
Research Use Only