Product Description

CDKN2A/p16INK4a Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB10721-50, MB10721-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Acts as a negative regμlator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.CautionThe proteins described here are encoded by the gene CDKN2A, but are completely unrelated in terms of sequence and function to tumor suppressor ARF (AC Q64364) which is encoded by the same gene.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: Cdkn2a, P16ink4a, Cyclin-dependent kinase 4 inhibitor A (CDK4I), p16-INK4a , p16-INK4

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of mouse CDKN2A/p16INK4a

Dilution: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 18 kDa, Observed MW: 18 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P51480

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only