CDKN2D Polyclonal Antibody - E-AB-61210

CDKN2D Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-61210-60, E-AB-61210-120, E-AB-61210-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CDKN2D

Target Synonym: CDKN2D; INK4D; p19; p19-INK4D

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P55273

Background: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CDKN2D (NP_001791.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only