CDKN3 Polyclonal Antibody - BT-AP07568

CDKN3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07568-20, BT-AP07568-50, BT-AP07568-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Cell biology; Signal transduction

Target Protein: CDKN3

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Cyclin-dependent kinase inhibitor 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q16667; Mouse: Q810P3; Rat: B2RZ50

Synonyms: Cyclin-dependent kinase inhibitor 3;EC 3.1.3.16;EC 3.1.3.48;CDK2-associated dual-specificity phosphatase;Cyclin-dependent kinase interactor 1;Cyclin-dependent kinase-interacting protein 2;K; Cyclin-dependent kinase inhibitor 3; EC 3.1.3.16; EC 3.1.3.48; CDK2-associated dual-specificity phosphatase; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; Kinase-associated phosphatase

GeneID: Human: 1033; Mouse: 72391

Research Use Only