Product Description

CDT2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10723-50, MB10723-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9NZJ0

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 79 kDa; Observed MW: 79 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CDT2 in Hela lysates using CDT2 antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CDT2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: CDW1; DCAF2; Dtl; L2DTL; RAMP

Immunogen: Recombinant protein of human CDT2

Conjugate: Unconjugated

Modification: Unmodified