Product Description

CDT2 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16920-50, BZ16920-100

Swiss-Prot: Q9NZJ0

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Background: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX (DTL) complex, also named CRL4 (CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21 (CIP1).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 79 kDa; Observed MW: 91 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CDT2 in 293T lysates using CDT2 antibody.

Alternative Name: CDW1; DCAF2; Dtl; L2DTL; RAMP

Immunogen: A synthesized peptide derived from human CDT2

Conjugate: Unconjugated

Modification: Unmodified